A Factor Analysis Model for Dimension Reduction of Outcome Factors in Neonatal Seizure Context

Authors

  • Ionela Maniu Pediatric Clinical Hospital, Sibiu & Lucian Blaga University of Sibiu
  • George Maniu Lucian Blaga University of Sibiu
  • Cristina Dospinescu Pediatric Clinical Hospital, Sibiu
  • Gabriela Visa Pediatric Clinical Hospital, Sibiu

Keywords:

neonatal seizures, risk factors, epilepsy, mortality, logistic regression, decision tree

Abstract

There is a controversial concept among many studies whether neonatal seizures are risk factors for neonatal death and/or neurodevelopment impairments (in case of newborn survivors). Multiple factors have been analyzed in literature, including perinatal factors, etiology factors, seizures characteristics factors, investigations findings factors, therapy-related factors. This paper aims to review the characteristics and the application context of different computational models developed for identifying both the risk factor of morbidity (epilepsy, cerebral palsy, development disability or their combination) and the mortality outcome after neonatal seizures. Consequently, we determined the groups of main risk factors using factor analysis. The vast majority of identified models are logistic regression models, but also decision tree models. In the literature, there is a large variation in establishing the risk factors determining poor or favorable outcome after a neonatal seizure, with similarities and inconsistencies. These findings could be a consequence of different approaches regarding inclusion criteria, methodologies used to identify seizure, seizures definition or description, analysis using computational models.

Author Biographies

Ionela Maniu, Pediatric Clinical Hospital, Sibiu & Lucian Blaga University of Sibiu

Ionela Maniu
Research and Telemedicine Center in Neurological Diseases in Children,
Pediatric Clinical Hospital, Sibiu, Romania
3 George Bari?iu, 550178, Tel. 0269 230 250
Department of Mathematics and Computer Science, ?Lucian Blaga? University, Sibiu, Romania
Bulevardul Victoriei 10, Sibiu 550024, Tel.: 0269 216 062
ionela.maniu@yahoo.ro

George Maniu, Lucian Blaga University of Sibiu

George Maniu
Department of Mathematics and Computer Science, ?Lucian Blaga? University , Sibiu, Romania
10 Bulevardul Victoriei, 550024, Tel.: 0269 216 062
george.maniu@ulbsibiu.ro

Cristina Dospinescu, Pediatric Clinical Hospital, Sibiu

Cristina Dospinescu

Research and Telemedicine Center in Neurological Diseases in Children,
Pediatric Clinical Hospital, Sibiu, Romania
3 George Bari?iu, 550178, Tel. 0269 230 250
cristinadospinescu@yahoo.com

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Gabriela Visa, Pediatric Clinical Hospital, Sibiu

Gabriela Visa

Research and Telemedicine Center in Neurological Diseases in Children,
Pediatric Clinical Hospital, Sibiu, Romania
3 George Bari?iu, 550178, Tel. 0269 230 250
gabiap@yahoo.com

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Published

2018-05-08

How to Cite

Maniu, I., Maniu, G., Dospinescu, C., & Visa, G. (2018). A Factor Analysis Model for Dimension Reduction of Outcome Factors in Neonatal Seizure Context. BRAIN. Broad Research in Artificial Intelligence and Neuroscience, 9(2), pp. 95-103. Retrieved from https://lumenpublishing.com/journals/index.php/brain/article/view/2036

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