Somatic Complications of Alcoholism in the Surgical Patient

Authors

  • Dragos F. Voicu Faculty of Medicine and Pharmacy, “Dunarea de Jos” University, Galati – Romania; County Emergency Hospital Braila, Romania
  • Alexandru Bogdan Ciubara Faculty of Medicine and Pharmacy, “Dunarea de Jos” University, Galati – Romania
  • Dorina Stan Faculty of Medicine and Pharmacy, “Dunarea de Jos” University, Galati – Romania
  • Anamaria Ciubara Faculty of Medicine and Pharmacy, “Dunarea de Jos” University, Galati – Romania

DOI:

https://doi.org/10.18662/brain/11.1Sup1/31

Keywords:

alcoholism, surgical patient

Abstract

Background. Alcoholism is a public health problem. Chronic ethanol consumption determines physiological and morphological changes, reflected by an abnormal response to regular medication and nutrients, with consequences on the efficiency of anesthesia and the surgical act.

Material and methods. A retrospective study was conducted on the latest 1750 cases (2016-2018), hospitalized and operated, in which the preoperative identification of alcohol abuse was made by dosing biochemical markers (gamma-glutamyl transferase, poor carbohydrate transferrin and medium erythrocytic corpuscular volume), by standard questionnaires and, of course, by preanesthetic exam.

Results and discussions. The study showed a rate of 8% (140 cases) of alcohol abuse among these surgical patients. The paper reviews the somatic complications of alcoholism: neurological, gastrointestinal, cardiovascular, metabolic, hematological, immunological and hormonal, and discusses the effectiveness of the study method.

Conclusions. It is proposed to implement a preoperative identification protocol for patients with alcoholism to prevent postoperative withdrawal.

Author Biographies

Dragos F. Voicu, Faculty of Medicine and Pharmacy, “Dunarea de Jos” University, Galati – Romania; County Emergency Hospital Braila, Romania

Faculty of Medicine and Pharmacy, “Dunarea de Jos” University, Galati – Romania; County Emergency Hospital Braila, Romania

Alexandru Bogdan Ciubara, Faculty of Medicine and Pharmacy, “Dunarea de Jos” University, Galati – Romania

Faculty of Medicine and Pharmacy, “Dunarea de Jos” University, Galati – Romania

Dorina Stan, Faculty of Medicine and Pharmacy, “Dunarea de Jos” University, Galati – Romania

Faculty of Medicine and Pharmacy, “Dunarea de Jos” University, Galati – Romania

Anamaria Ciubara, Faculty of Medicine and Pharmacy, “Dunarea de Jos” University, Galati – Romania

Faculty of Medicine and Pharmacy, “Dunarea de Jos” University, Galati – Romania

References

Andresen-Streichert, H., Müller, A., Glahn, A., Skopp, G., & Sterneck, M. (2018). Alcohol biomarkers in clinical and forensic contexts. Deutsches Aerzteblatt Online, 115(18), 309–315. https://doi.org/10.3238/arztebl.2018.0309

Bagnardi, V., Rota, M., Botteri, E., Tramacere, I., Islami, F., Fedirko, V., Scotti, L., Jenab, M., Turati, F., Pasquali, E., Pelucchi, C., Galeone, C., Bellocco, R., Negri, E., Corrao, G., Boffetta, P., & La Vecchia, C. (2015). Alcohol consumption and site-specific cancer risk: A comprehensive dose–response meta-analysis. British Journal of Cancer, 112(3), 580-593. https://doi.org/10.1038/bjc.2014.579

Chitescu, C. L., Radu, A. D., Aciu, F., & Moraru, M. (2018). New psychoactive substances (NPSs) abuse in Romania: Analytical strategies for drug screening in biological samples using high resolution mass spectrometry. Romanian Journal of Legal Medicine, 26(2), 173-182.

Clero, J. (2018). Medicine, robot and intimacy. Journal for Ethics in Social Studies, 2(1), 1-21. http://dx.doi.org/10.18662/jess/06

Damian, S., Diac, M., Iov, T., Hunea, I., & Bulgaru Iliescu, D. (2019). Particularities of medical education in the field of forensic toxicology. Studying dangerous chemical agents in forensic research. Revista Romaneasca pentru Educatie Multidimensionala, 11(4Sup1), 337-344. http://dx.doi.org/10.18662/rrem/194

De Meneses-Gaya, C., Zuardi, A. W., Loureiro, S. R., & Crippa, J. A. S. (2009). Alcohol Use Disorders Identification Test (AUDIT): An updated systematic review of psychometric properties. Psychology & Neuroscience, 2(1), 83-97. http://dx.doi.org/10.3922/j.psns.2009.1.12

Engen, P. A., Green, S. J., Voigt, R. M., Forsyth, C. B., & Keshavarzian, A. (2015). The gastrointestinal microbiome: Alcohol effects on the composition of intestinal microbiota. Alcohol Research, 37(2), 223-236. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/26695747

Gardner, J. D., & Mouton, A. J. (2015). Alcohol effects on cardiac function. Comprehensive Physiology, 5(2), 791-802. https://doi.org/10.1002/cphy.c140046

Jastrzebska, I., Zwolak, A., Szczyrek, M., Wawryniuk, A., Skrzydlo-Radomanska, B., & Daniluk, J. (2016). Biomarkers of alcohol misuse: Recent advances and future prospects. Gastroenterology Review, 11(2), 78–89. https://doi.org/10.5114/pg.2016.60252

Kummer, N., Lambert, W. E., Samyn, N., & Stove, C. P. (2016). Alternative sampling strategies for the assessment of alcohol intake of living persons. Clinical Biochemistry, 49(13-14), 1078-1091. https://doi.org/10.1016/j.clinbiochem.2016.05.007

Mihok-Geczi, I., & Hatos, A. (2019). The risk of relapse following abstinence in case of alcohol abuse disorder: the importance of relational and normative support. Postmodern Openings, 10(2), 28-56. http://dx.doi.org/10.18662/po/70

Mirijello, A., D'Angelo, C., Ferrulli, A., Vassallo, G., Antonelli, M., Caputo, F., Leggio, L., Gasbarrini, A., & Addolorato, G. (2015). Identification and management of alcohol withdrawal syndrome. Drugs, 75(4), 353–365. https://doi.org/10.1007/s40265-015-0358-1

Mo, Y., Thomas, M. C., Laskey, C. S., Shcherbakova, N., Bankert, M. L., & Halloran, R. H. (2018). Current practice patterns in the management of alcohol withdrawal syndrome. Pharmacy and Therapeutics, 43(3), 158–162. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/29491698

Noble, J. M., & Weimer, L. H. (2014). Neurologic complications of alcoholism. Neurology of Systemic Disease, 20(3), 624-641. https://doi.org/10.1212/01.con.0000450970.99322.84

Osaki, Y., Kinjo, A., Higuchi, S., Matsumoto, H., Yuzuriha, T., Horie, Y., Kimura, M., Kanda, H., & Yoshimoto, H. (2016). Prevalence and trends in alcohol dependence and alcohol use disorders in Japanese adults; results from periodical nationwide surveys. Alcohol and Alcoholism, 51(4), 465–473. https://doi.org/10.1093/alcalc/agw002

Ratna, A., & Mandrekar, P. (2017). Alcohol and cancer: Mechanisms and therapies. Biomolecules, 7(3), 61. https://doi.org/10.3390/biom7030061

Rehm, J., Taylor, B., Mohapatra, S., Irving, H., Baliunas, D., Patra, J., & Roerecke, M. (2010). Alcohol as a risk factor for liver cirrhosis: A systematic review and meta-analysis. Drug and Alcohol Review, 29(4), 437-445. https://doi.org/10.1212/01.con.0000450970.99322.84

Ren, J., & Wold, L. E. (2008). Mechanisms of alcoholic heart disease. Therapeutic Advances in Cardiovascular Disease, 2(6), 497–506. https://doi.org/10.1177/1753944708095137

Rumpf, H.-J., Hapke, U., Meyer, C., & John, U. (2002). Screening for alcohol use disorders and at-risk drinking in the general population: Psychometric performance of three questionnaires. Alcohol and Alcoholism, 37(3), 261-268. https://doi.org/10.1093/alcalc/37.3.261

Sandu, A. (2018). A philosophical rethinking of medical ethics. Logos Universality Mentality Education Novelty: Philosophy & Humanistic Sciences, 6(1), 28-31. http://dx.doi.org/10.18662/lumenphs/03

Schuckit, M. A. (2009). Alcohol - related disorders. In: B. J. Sadock, V. A. Sadock, P. Ruiz (Eds.), Kaplan and Sadock s comprehensive textbook of psychiatry (9th ed., vol. 1, pp. 1268 – 1288). Wolters Kluwer/Lippincott Williams & Wilkins.

Sullivan, E. V., Harris, R. A., & Pfefferbaum, A. (2010). Alcohol's effects on brain and behavior. Alcohol Research & Health, 33(1-2), 127–143. Retrieved from https://psycnet.apa.org/record/2010-23622-013

Torrente, M. P., Freeman, W. M., & Vrana, K. E. (2019). Protein biomarkers of alcohol abuse. Expert Review of Proteomics, 9(4), 425–436. https://doi.org/10.1586/epr.12.38

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Published

2020-04-14

How to Cite

Voicu, D. F., Ciubara, A. B., Stan, D., & Ciubara, A. (2020). Somatic Complications of Alcoholism in the Surgical Patient. BRAIN. Broad Research in Artificial Intelligence and Neuroscience, 11(1Sup1), 78-89. https://doi.org/10.18662/brain/11.1Sup1/31

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