Latent Aggression and Impulsive Manifestations of the Psychiatric Patient. Clinical, Legal and Ethical Aspects


  • Codrina MORARU Second Year Medical Resident in psychiatry, “Socola” Psychiatry Institute, Iași
  • Ionuț-Dragoș RADULESCU MD, Specialist in psychiatry, “Elisabeta Doamna” Psychiatry Hospital, Galați
  • Alina Ioana VOINEA LAS CT, Hertfordshire Partnership University NHS Foundation Trust, St. Albans, United Kingdom
  • Mirona Letiția DOBRI Third Year Medical Resident in psychiatry, “Socola” Psychiatry Institute, Iași
  • Gabriela RUSU-ZOTA MD, PhD, Lecturer, Department of Pharmacology – Algesiology, Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iași
  • Petronela NECHITA MD, PhD, Senior psychiatrist, “Socola” Psychiatry Institute, Iași



aggressive manifestations, psychiatric diagnosis, social reintegration


Psychiatry represents the medical branch that focuses not only on the patient’s mental state but also on general health issues and wellbeing. With the continuous development of human civilization, the individual no longer uses aggression, a counterproductive method for day to day living in the community, to meet its basic needs. Neurobiological changes that lead to aggressive manifestations are a medical problem only if the aggressive impulses occur in a person with a psychiatric diagnosis already established and poses a danger to himself and others. Aggressive behaviour due to a medical condition or biological factors is an old problem that has great forensic implications both for the patient and for the medical staff. Decreased quality of life, low emotional support and social marginalization are some of the repercussions that emerge. Understanding the negative effects of aggressive impulses found in multiple psychiatric diagnoses is the key to an optimal doctor-patient relationship. An individualized treatment is necessary, the final goal being social reintegration.


Archer, J. (2009). The nature of human aggression. International Journal of Law and Psychiatry, 32(4), 202–208.

Barlow, D. H. (2002). Anxiety and Its Disorders: The Nature and Treatment of Anxiety and Panic (2nd Edition). Guilford.

Barratt, E. S., Stanford, M. S., Felthous, A. R., Matthew, S., Felthous, A. R., & Kent, T. A. (1997). The effects of phenytoin on im- pulsive and premeditated aggression: a controlled study. Journal of Clinical Psychopharmacology, 17(5), 341-349.

Bolos, A., Ciubara, A-M., & Chirita, R. (2012). Moral And Ethical Aspects Of The Relationship Between Depression And Suicide. Revista Romana de Bioetica, 10(3), 71-79.

Bulgaru-Iliescu, D., Costea, G., Scripcaru, A., & Ciubara, A-M. (2015). Homicide and alcohol consumption. A medico-legal and psychiatric interdisciplinary approach. Multivariate analysis. Romanian Journal Of Legal Medicine, 23(2), 137-142.

Cardinal, R. N., Parkinson, J. A., Hall, J., & Everitt, B. J. (2002). Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex. Neuroscience & Biobehavioral Reviews, 26(3), 321–352.

Cherek, D. R., Tcheremissine, O. V., & Lane, S. D. (2006). Psychopharmacology of aggression. In: Nelson RJ, editor. Biology of aggression. Oxford University Press.

Chirita, R., Sacuiu, I., Burlea, A., & Chirita, V. (2012). The role of nitric oxide inhibitors in treatment on symptom severity and cognitive deficits in schizophrenia. International Journal Of Neuropsychopharmacology, 15, 113-113.

Ciobotea, D., Vlaicu, B., Ciubara, A., Duica, C.L., Cotocel, C., Antohi, V., Pirlog, M.C. (2016). Visual Impairment in the Elderly and its Influence on the Quality of Life. Revista de Cercetare si Interventie Sociala, 54, 66-74.

Ciubara, A. B., Tudor, R. C., Nechita, L., Tita, O., Ciubara, A. M., Turliuc, S., & Raftu, G. (2018). The Composition of Bioactive Compounds in Wine and Their Possible Influence on Osteoporosis and on Bone Consolidation. Revista de Chimie, 69(5), 1247-1253.

Ciubara, A., Chirita, R., Burlea, L.S., Lupu, V.V., Mihai, C., Moisa, S. M., Untu, I. (2016). Psychosocial Particularities of Violent Acts in Personality Disorders. Revista de Cercetare si Interventie Sociala, 52, 265-272.

Ciubara, A-M., Burlea, S. L., Sacuiu, I., Radu, D. A., Untu, I., & Chirita, R. (2015). Alcohol addiction - a psychosocial perspective.‏ Procedia Social and Behavioral Sciences, 187, 536-540.

Dumbrava, D. P., Radu, C. C., Chiroban, O., Bulgaru-Iliescu, D., Iov, T., Damian, S-I., & Ureche, D. (2019). Retrograde Extrapolation of Blood Alcohol Concentration A theoretical and practical approach. Revista de Chimie, 70(2), 407-409.

Diac, M., Oprea, R., Iov, T., Damian, S-I., Knieling, A., & Bulgaru-Iliescu, A-I. (2020). Finite Elements Models of the Head in Craniocerebral Trauma – Review. BRAIN. Broad Research in Artificial Intelligence and Neuroscience, 11(1Sup1), 08-21.

Fernandez, E., & Johnson, S. L. (1990). Anger in psychological disorders: prevalence, presentation, etiology and prognostic implications. Clinical Psychology, 46, 124-135.

Fisher, R., Van Emde Boas, W., Blume, W., Elger, C., Genton, P., Lee, P., & Engel, J. (2005). Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia, 46(4), 470–472.

George, D. T., Rawlings, R. R., Williams, W. A., Phillips, M. J., Fong, G., Kerich, M., Momenan, R., Umhau, J. C., & Hommer, D. (2004). A select group of perpetrators of domestic violence: evidence of decreased metabolism in the right hypothalamus and reduced relationships between cortical/subcortical brain structures in position emission tomography. Psychiatry Research, 130(1), 11–25.

Gorney, B. (1989). Domestic violence and chemical dependency: dual problems dual interventions. Journal of Psychoactive Drugs, 21(2), 229-238.

Hammer, G. D., McPhee, S. J. (eds.), (2010). "7". Pathophysiology of disease : an introduction to clinical medicine (6th ed.). McGraw-Hill Medical.

Harenski, K. A., Thornton, D. M., Harenski, K. A., Decety, J., & Kiehl, K. A. (2012). Increased frontotemporal activation during pain observation in sexual sadism preliminary findings. Archives Of General Psychiatry, 69(3), 283-292.

Livingston, G., Sommerlad, A., Orgeta, V., Costafreda, S. G., Huntley, J., Ames, D., Kivimäki, M., Larson, E. B., Ogunniyi, A., Orgeta, V., Ritchie, K., Rockwood, K., Sampson, E. L., Samus, Q., Schneider,L. S., Selbæk, G., Teri, L., & Mukadam, N. (2017). Dementia prevention, intervention, and care. The Lancet, 390(10113), 2673–2734.

Marcangelo, M. J., & Ovsiew, F. (2007). Psychiatric aspects of epilepsy. Psychiatric Clinics of North America, 30(4), 781–802.

Miles, D. R., & Carey, G. (1997). Genetic and environmental architecture of human aggression. Journal of Personality and Social Psychology, 72(1), 207-217.

Moscovitch, D. A., McCabe, R. E., Antony, M. M., Rocca, L., & Swinson, R. P. (2008). Anger experience and expression across the anxiety disorders. Depression Anxiety, 25(2), 107-113.

Murray-Close, D., Ostrov, J. M., Nelson, D. A., Crick, N. R., & Coccaro, E. F. (2010). Proactive, reactive, and ro- mantic relational aggression in adulthood: measurement, predictive va lidity, gender differences, and association with intermittent disorder. Journal of Psychiatric Research, 44(6), 393–404.

New, A. S., Hazlett, E. A., Buchsbaum, M. S., Goodman, M., Reynolds, D., Mitropoulou, V., Sprung, L., Shaw Jr, R. B., Koenigsberg, H., Platholi, J., Silverman, J., & Siever, L. J. (2002). Blunted prefrontal cortical 18fluorodeoxyglucose positron emission tomography response to meta-chlorophenylpiperazine in impulsive aggression. Archives Of General Psychiatry, 59(7), 621–629.

Perlis, R. H., Smoller, J. W., Fava, M., Rosenbaum, J. F., Nierenberg, A. A., & Sachs, G. S. (2004). The prevalence and clinical correlates of anger attacks during depressive episodes in bipolar disorder. Journal of Affective Disorders, 79(1-3), 291-295.

Raine, A., Meloy, J. R., Bihrle, S., Stoddard, J., LaCasse, J., & Buchsbaum, M. S. (1998). Reduced prefrontal and increased subcortical brain functioning assessed using positron emission tomography in predatory and affective murderers. Behavioral Sciences & the Law, 16(3), 319-332.<319::aid-bsl311>;2-g

Untu, I., Chirita, R., Bulgaru-Iliescu, D., Chirila, B. D., Ciubara, A., & Burlea, S. L. (2015). Ethical Implications of Bio-Psycho-Social Transformations Entailed by the Aging Process. Revista de Cercetare si Interventie Sociala, 48, 216-225.

Valcea, L., Bulgaru-Iliescu, D., Burlea, S. L., & Ciubara, A. (2016). Patient’s rights and communication in the hospital accreditation process. Revista de Cercetare si Interventie Sociala, 55, 260-270.

Volkow, N. D., Tancredi, L. R., Grant, C., Gillespie, H., Valentine, A., Mullani, N., Wanga, G-J., & Hollister, L. (1995). Brain glucose metabolism in violent psychiatric patients: a preliminary study. Psychiatry Research, 61(4), 243– 253.

Walsh, E., Buchannan, A., & Fahy, T. (2001). Violence and schizophrenia: examining the evidence. The British Journal of Psychiatry, 180, 490–495.

World Health Organization. (2007). WHO Expert Committee on Problems Related to Alcohol Consumption, Second Report. World Health Organization, Geneva.

Yeh, M. T., Coccaro, E. F., & Jacobson, K. C. (2010). Multivariate Behavior Genetic Analyses of Aggresive Behavior Subtipes. Behavior Genetics, 40, 603-617.




How to Cite

MORARU, C., RADULESCU, I.-D., VOINEA, A. I. ., DOBRI, M. L. ., RUSU-ZOTA, G. ., & NECHITA, P. (2020). Latent Aggression and Impulsive Manifestations of the Psychiatric Patient. Clinical, Legal and Ethical Aspects. BRAIN. Broad Research in Artificial Intelligence and Neuroscience, 11(3Sup1), 220-230.

Most read articles by the same author(s)

Publish your work at the Scientific Publishing House LUMEN

It easy with us: publish now your work, novel, research, proceeding at Lumen Scientific Publishing House

Send your manuscript right now