Etiological Factors and Parental Coping in Congenital Heart Malformations

Authors

  • Stefana Moisa “Grigore T. Popa” University of Medicine and Pharmacy, Pediatrics Department, Iasi, Romania, “Sfanta Maria” Clinical Emergency Hospital, Iasi, Romania
  • Lacramioara Butnariu “Sfanta Maria” Clinical Emergency Hospital, Iasi, Romania “Grigore T. Popa” University of Medicine and Pharmacy, Microbiology Department, Iasi, Romania
  • Carmen Valerica Ripa “Grigore T. Popa” University of Medicine and Pharmacy, Microbiology Department, Iasi, Romania
  • Roxana Gabriela Cobzaru “Grigore T. Popa” University of Medicine and Pharmacy, Microbiology Department, Iasi, Romania
  • Laura Trandafir Grigore T. Popa” University of Medicine and Pharmacy, Pediatrics Department, Iasi, Romania; “Sfanta Maria” Clinical Emergency Hospital, Iasi, Romania

DOI:

https://doi.org/10.18662/brain/15.1/547

Keywords:

congenital heart malformation, mutation, genetic abnormality, coping

Abstract

The etiology of congenital heart malformations is still insufficiently known. Many genetic mutations exert their action through various mechanisms on neural crest signaling, acting on neural cell migration and altering bulboconal region formation or resorbtion. Some studies evaluate the role of punctual or noncoding mutations, while others highlight the teratogen effect of retinoic acid or ethanol, or discuss the role of maternal diabetes or pregnancy rubella. The etiology of congenital heart malformations is complex and multifactorial and requires further studies. The impact on the family of a child with a congenital heart malformation is significant and various coping mechanisms are employed by parents to address the issue.

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Published

2024-02-06

How to Cite

Moisa, S., Butnariu, L., Ripa, C. V., Cobzaru, R. G., & Trandafir, L. (2024). Etiological Factors and Parental Coping in Congenital Heart Malformations. BRAIN. Broad Research in Artificial Intelligence and Neuroscience, 15(1), 220-228. https://doi.org/10.18662/brain/15.1/547

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