Examination on the Effect of Swimming Exercises Applied with Co Enzyme Q10 and Zinc Supplementation on the Ast-Alt Metabolism in Young Athletes
Keywords:Zinc, CoQ10, AST and ALT, swimming,
In that study, it has been aimed to determine the effect of zinc and CoQ10 supplementation applied with 8-week swimming exercises on AST-ALT metabolism.
Our study was conducted on 36 voluntary male athletes aged 18-22 who do physical exercises actively. The participants were divided equally into 4 groups. The groups were constituted in that way: 1st Group: Group which is supplied with zinc (Z), 2nd Group: Group which is supplied with Coenzyme Q10 (Q), 3rd Group: Control Group who does physical exercises (C) and 4th Group: Group which is supplied with Zinc and Coenzyme Q10 (ZQ). At the first week of the study, AST and ALT levels of the participants were measured from the samples which were drawn from the participants at pre-exercise resting period (PRP), post-exercise pre-test fatigue (PTF) and pre-exercise post-test rested (PTR) and post-exercise post-test fatigue (PTF) after 8-week supplementation period. In consequence of the conducted analysis, it was identified that rested AST levels of the group supplied with zinc were higher than their fatigue levels after 8-week supplementation period (p<0.05). As for ALT values of the group supplied with zinc, the post-test fatigue values were found lower than the pre-exercise rested and after 8-week exercise rested values (p<0.05). The post-test fatigue (PTF) values of the control group were determined lower than their post-test rested (PTR) values (p<0.05). It was identified statistically significant differences between not only PostTF and PostTR values but also PostTR and PreTR values of the group supplied with Zinc and Coenzyme Q10 (p<0.05). Consequently, it was confirmed that zinc and CoQ10 supplementation applied with 8-week swimming exercises had influence over the AST and ALT metabolism. It can be said that the antioxidant supplementation makes significant contributions as the AST and ALT metabolism are active.
American Dietetic Association. (2003). Position of the American Dietetic Association and Dietitians of Canada: Vegetarian diets. Journal of the Academy of Nutrition and Dietetics, 103(6), 748. doi:10.1053/jada.2003.50142
American Dietetic Association. (2009). Position of the American Dietetic Association, Dietitians of Canada, and the College of Sports Medicine: Nutrition and athletic performance. Journal of the American Dietetic Association, 109(3), 509-526. doi:10.1016/j.jada.2009.01.005
Baltaci, A. K., Ozyurek, K., Mogulkoc, R., Kurtoglu, E., Oztekin, E., & Kul, A. (2003). Effects of zinc deficiency and supplementation on some hematologic parameters of rats performing acute swimming exercise. Acta Physiological Hungarica, 90(2), 125-132. doi:10.1556/aphysiol.90.2003.2.5
Bezci, Ş. (2007). The analyze of hematological and biological parameters of elite taekwondoers before and after training. Master Thesis. Konya, Turkey: University of Selcuk.
Braun, B., Clarkson, P. M., Freedson, P. S., & Kohl, R. L. (1991). Effects of coenzyme Q10 supplementation on exercise performance, VO2max, and lipid peroxidation in trained cyclists. International Journal of Sport Nutrition, 1(4), 353-365. doi:10.1123/ijsn.1.4.353
Burris, C. A., Ashwood, E. R., & Burns, D. E. (2006). Tietz textbook of clinical chemistry and molecular diagnostics (4th ed.). St. Louis, USA: Elsevier Saunders.
Champe, P., & Harvey, R. (1997). Biochemistry (2nd ed.). Philadelphia, USA: Lippincott Williams & Wilkins.
Clarkson, P. M., Kearns, A. K., Rouzier, P., Rubin, R., & Thompson, P. D. (2006). Serum creatine kinase levels and renal function measures in exertional muscle damage. Medicine & Science in Sports and Exercise, 38(4), 623–627. doi:10.1249/01.mss.0000210192.49210.fc
Cooke, M., Iosia, M., Buford, T., Shelmadine, B., Hudson, G., Kerksick, C., Rasmussen, C., Greenwood, M., Leutholtz, B., Willoughby, D., & Kreider, R. (2008). Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. Journal of the International Society of Sports Nutrition, 5(1), e8. doi:10.1186/1550-2783-5-8
Fallon, K. E., Sivyer, G., Sivyer, K., & Dare, A. (1999). The biochemistry of runners in a 1600 km ultramarathon. British Journal of Sports Medicine, 33(4), 264-269. doi:10.1136/bjsm.33.4.264
Fallon, K. E. (2008). The clinical utility of screening of biochemical parameters in elite athletes: analysis of 100 cases. British Journal of Sports Medicine, 42(5), 334-337. doi:10.1136/bjsm.2007.041137
Giboney, P. T. (2005). Mildly elevated liver transaminase levels in the asymptomatic patient. American Family Physician, 71(6), 1105-1110.
Gürkan, A. S., & Bozdağ-Dündar, O. (2005). Coenzyme Q10. Journal of Faculty of Pharmacy of Ankara, 34(2), 129-54.
Hyo, J. K., Yoon, H. L., & Chang, K. K. (2007). Biomarkers of muscle and cartilage damage and inflammation during a 200 km run. European Journal of Applied Physiology, 99(4), 443–447. doi:10.1007/s00421-006-0362-y
Kara, E., Gunay, M., Cicioglu, I., Ozal, M., Kilic, M., Mogulkoc, R., & Baltaci, A. K. (2010). Effect of zinc supplementation on antioxidant activity in young wrestlers. Biological Trace Element Research, 134(1), 55-63. doi:10.1007/s12011-009-8457-z
Mancini, A., Festa, R., Raimondo, S., Pontecorvi, A., & Littarru, G.P. (2011). Hormonal influence on coenzyme Q10 levels in blood plasma. International Journal of Molecular Sciences, 12(12), 9216-9225. doi:10.3390/ijms12129216
Mashiko, T., Umeda, T., Nakaji, S., & Sugawara, K. (2004). Effects of exercise on the physical condition of college rugby players during summer training camp. British Journal of Sports Medicine, 38(2), 186-190. doi:10.1136/bjsm.2002.004333
Mena, P., Maynar, M., & Campillo, J. E. (1996). Changes in plasma enzyme activities in professional racing cyclists. British Journal of Sports Medicine, 30(2), 122-124. doi:10.1136/bjsm.30.2.122
Murray, R., Granner, D., Mayes, P., & Rodwell, W. (1996). Harper’s Biochemistry (24th ed.). Upper Saddle River, USA: Prentice Hall International.
Nie, J., Tong, T. K., George, K., Fu, F. H., Lin, H., & Shi, Q. (2011). Resting and post-exercise serum biomarkers of cardiac and skeletal muscle damage in adolescent runners. Scandinavian Journal of Medicine & Science in Sports, 21(5), 625–629. doi:10.1111/j.1600-0838.2010.01096.x
Pathak, R., Dhawan, D., & Pathak, A. (2011). Effect of zinc supplementation on the status of thyroid hormones and Na, K, and Ca levels in blood following ethanol feeding. Biological Trace Element Research, 140(2), 208–214. doi:10.1007/s12011-010-8691-4
Polat, Y. (2011). Effects of zinc supplementation on hematological arameters of high performance athletes. African Journal of Pharmacy and Pharmacology, 5(12), 1436-1440. doi:10.5897/ajpp11.062
Prasad, A. S. (1982). Clinical, biochemical and nutritional aspects of zinc. Annual Review of Pharmacology and Toxicology, 20, 267–270.
Rosmarin, M. N., Beard, M. J., & Robbins, S. W. (1993). Serum enzyme activities in individuals with different levels of physical fitness. The Journal of Sports Medicine and Physical Fitness, 33(3), 252-257.
Skenderi, K. P., Kavouras, S. A., Anastasiou, C. A., Yiannakouris, N., & Matalas, A. (2006). Exertional rhabdomyolysis during a 246-km continuous running race. Medicine Science in Sports Exercise, 38(6), 1054-1057. doi:10.1249/01.mss.0000222831.35897.5f
Su, Y. C., Lin, C. J., Chen, K. T., Lee, S. M., Lin, J. S., Tsai, C. C., Lin, J. G. (2001). Effects of huangqi jianzhong tang on hematological and biochemical parameters in judo athletes. ACTA Pharmacologica sinica, 22(12), 1154-1158.
Taneli, B. (2005). Zinc in Anatolian population. Ege Tıp Dergisi, 44(1), 1-10.
Torlak, Ş., Okudan, N., Gökbel, H., Belviranlı, M., & Kıyıcı, A. (2012). The effect of 4-week CoQ10 supplementation on the exercise-induced muscle injury sedantary young men. General Medicine, 22(1).
Uygun, A., & Polat, Z. (2009). Diseases that causes increases in viral non hepatitis serum transaminase level. Current gastroenterology, 13(4), 211-216.
Wu, H., Chen, K., Shee, B., Huang, Y., & Yang, R. (2004). Effects of 24 H ultra marathon on biochemical and hematologicial parameters. World Journal of Gastroenterology, 10(18), 2711-2714. doi:10.3748/wjg.v10.i18.2711
Zhou, S., Zhang, Y., Davie, A., Marshall-Gradisnik, S., Hu, H., Wang, J., & Brushett, D. (2005). Muscle and plasma coenzyme Q10 concentration, aerobic power and exercise economy of healthy men in response to 27four weeks of supplementation. Journal of Sports Medicine and Physical Fitness, 45(3), 337-46.
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